Orbital implant exposure after Acanthamoeba panophthalmitis

Meredith S. Baker, Amanda C. Maltry, Nasreen A. Syed, Richard C. Allen

Research output: Contribution to journalArticle

Abstract

Purpose: Acanthamoeba is a protozoa that can lead to severe ocular disease and sequelae. Although intraocular Acanthamoeba infection is rare, the following case demonstrates an unusual presentation of recurrent Acanthamoeba infection in a 30 year old contact lens wearing male. Observations: After presenting with recurrent Acanthamoeba keratitis and undergoing various treatments, the patient developed nodular scleritis, which evolved into panophthalmitis, and ultimately, required enucleation. Eight months post-operatively, the patient developed orbital implant exposure secondary to persistent Acanthamoeba infection and underwent removal of the implant and aggressive, systemic treatment involving a multispecialty care team. He then underwent placement of a dermis fat graft and had no signs of persistent infection at the time of last follow-up, which was 24 months after placement of the dermis fat graft. Conclusions: and Importance: To the authors' knowledge, this is the first known case of Acanthamoeba infection causing orbital implant exposure. Persistent infection should be considered in Acanthamoeba patients who have undergone enucleation and have orbital implant exposure. Better knowledge regarding the pathogenesis and extracorneal complications of this challenging disease may improve patient care and outcomes.

Original languageEnglish (US)
Pages (from-to)48-50
Number of pages3
JournalAmerican Journal of Ophthalmology Case Reports
Volume10
DOIs
StatePublished - Jun 2018

Fingerprint

Panophthalmitis
Orbital Implants
Acanthamoeba
Infection
Dermis
Fats
Acanthamoeba Keratitis
Scleritis
Transplants
Eye Diseases
Contact Lenses
Patient Care
Therapeutics

Keywords

  • Acanthamoeba
  • Keratitis
  • Orbital implant exposure

PubMed: MeSH publication types

  • Journal Article

Cite this

Orbital implant exposure after Acanthamoeba panophthalmitis. / Baker, Meredith S.; Maltry, Amanda C.; Syed, Nasreen A.; Allen, Richard C.

In: American Journal of Ophthalmology Case Reports, Vol. 10, 06.2018, p. 48-50.

Research output: Contribution to journalArticle

Baker, Meredith S. ; Maltry, Amanda C. ; Syed, Nasreen A. ; Allen, Richard C. / Orbital implant exposure after Acanthamoeba panophthalmitis. In: American Journal of Ophthalmology Case Reports. 2018 ; Vol. 10. pp. 48-50.
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