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Oral rapamycin reduces tumour burden and vascularization in Lkb1
+/-
mice
James Robinson
, Cecilia Lai
, Alison Martin
, Emma Nye
, Ian Tomlinson
, Andrew Silver
Research output
:
Contribution to journal
›
Article
›
peer-review
45
Scopus citations
Overview
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Dive into the research topics of 'Oral rapamycin reduces tumour burden and vascularization in Lkb1
+/-
mice'. Together they form a unique fingerprint.
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Keyphrases
Rapamycin
100%
Tumor Burden
100%
Tumor Vascularization
100%
Liver Kinase B1 (LKB1)
100%
Polyps
57%
Peutz-Jeghers Syndrome
28%
Mammalian Target of Rapamycin (mTOR)
14%
Early Intervention
14%
Cancer Risk
14%
Murine Model
14%
Phosphorylation
14%
Tumor Suppressor Gene
14%
Therapeutic Effect
14%
Oral Administration
14%
Akt Phosphorylation
14%
Large Cohort
14%
P70S6K
14%
Tumor Incidence
14%
Antiangiogenic Properties
14%
Microvessel Density
14%
Macrolides
14%
Multiple Organs
14%
Germline mutation
14%
Polyposis
14%
Hamartomatous
14%
Gastric Tumor
14%
Intestinal Polyposis
14%
Antiangiogenic Activity
14%
Pharmacology, Toxicology and Pharmaceutical Science
Rapamycin
100%
Polyp
57%
Antiangiogenic
28%
Peutz Jeghers Syndrome
28%
Macrolide
14%
Tumor Suppressor Protein
14%
Cancer Incidence
14%
Therapeutic Effect
14%
S6 Kinase
14%
Stomach Tumor
14%
Gastrointestinal Polyposis
14%
Polyposis
14%
Serine
14%
Protein Kinase B
14%
Side Effect
14%
Oral Administration
14%