Ofloxacin (400 mg q12h) and cefaclor (250 to 500 mg q8h) were compared during a 7- to 14-day course of treatment in 98 patients with lower respiratory tract infections (LRTIs). Clinical cure or improvement occurred in 87.8% of patients in the ofloxacin group versus 81.6% in the cefaclor group. In the ofloxacin group, there was bacteriologic eradication of 85% of pathogens, compared with 48% of pathogens in the cefaclor group. Adverse events were reported hy a comparable proportion of patients in each treatment group.
|Original language||English (US)|
|Number of pages||6|
|Journal||Infections in Medicine|
|State||Published - Nov 8 1995|
- infection, respiratory tract