Oral ofloxacin versus cefaclor for LRTIs in adults

D. S. Dark; M. Farber; Kathryn L Rice; D. Levin; W. Merrill; M. Mufson; D. Pitrak; B. Varkey

Oral ofloxacin versus cefaclor for LRTIs in adults

D. S. Dark, M. Farber, Kathryn L Rice, D. Levin, W. Merrill, M. Mufson, D. Pitrak, B. Varkey

Research output: Contribution to journal › Article › peer-review

Abstract

Ofloxacin (400 mg q12h) and cefaclor (250 to 500 mg q8h) were compared during a 7- to 14-day course of treatment in 98 patients with lower respiratory tract infections (LRTIs). Clinical cure or improvement occurred in 87.8% of patients in the ofloxacin group versus 81.6% in the cefaclor group. In the ofloxacin group, there was bacteriologic eradication of 85% of pathogens, compared with 48% of pathogens in the cefaclor group. Adverse events were reported hy a comparable proportion of patients in each treatment group.

Original language	English (US)
Pages (from-to)	551-556
Number of pages	6
Journal	Infections in Medicine
Volume	12
Issue number	10
State	Published - 1995
Externally published	Yes

Keywords

bronchitis
cefaclor
infection, respiratory tract
ofloxacin
pneumonia

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title = "Oral ofloxacin versus cefaclor for LRTIs in adults",

abstract = "Ofloxacin (400 mg q12h) and cefaclor (250 to 500 mg q8h) were compared during a 7- to 14-day course of treatment in 98 patients with lower respiratory tract infections (LRTIs). Clinical cure or improvement occurred in 87.8% of patients in the ofloxacin group versus 81.6% in the cefaclor group. In the ofloxacin group, there was bacteriologic eradication of 85% of pathogens, compared with 48% of pathogens in the cefaclor group. Adverse events were reported hy a comparable proportion of patients in each treatment group.",

keywords = "bronchitis, cefaclor, infection, respiratory tract, ofloxacin, pneumonia",

author = "Dark, {D. S.} and M. Farber and Rice, {Kathryn L} and D. Levin and W. Merrill and M. Mufson and D. Pitrak and B. Varkey",

year = "1995",

language = "English (US)",

volume = "12",

pages = "551--556",

journal = "Infections in Medicine",

issn = "0749-6524",

publisher = "CMP Healthcare Media LLC",

number = "10",

}

TY - JOUR

T1 - Oral ofloxacin versus cefaclor for LRTIs in adults

AU - Dark, D. S.

AU - Farber, M.

AU - Rice, Kathryn L

AU - Levin, D.

AU - Merrill, W.

AU - Mufson, M.

AU - Pitrak, D.

AU - Varkey, B.

PY - 1995

Y1 - 1995

N2 - Ofloxacin (400 mg q12h) and cefaclor (250 to 500 mg q8h) were compared during a 7- to 14-day course of treatment in 98 patients with lower respiratory tract infections (LRTIs). Clinical cure or improvement occurred in 87.8% of patients in the ofloxacin group versus 81.6% in the cefaclor group. In the ofloxacin group, there was bacteriologic eradication of 85% of pathogens, compared with 48% of pathogens in the cefaclor group. Adverse events were reported hy a comparable proportion of patients in each treatment group.

AB - Ofloxacin (400 mg q12h) and cefaclor (250 to 500 mg q8h) were compared during a 7- to 14-day course of treatment in 98 patients with lower respiratory tract infections (LRTIs). Clinical cure or improvement occurred in 87.8% of patients in the ofloxacin group versus 81.6% in the cefaclor group. In the ofloxacin group, there was bacteriologic eradication of 85% of pathogens, compared with 48% of pathogens in the cefaclor group. Adverse events were reported hy a comparable proportion of patients in each treatment group.

KW - bronchitis

KW - cefaclor

KW - infection, respiratory tract

KW - ofloxacin

KW - pneumonia

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M3 - Article

AN - SCOPUS:0028863178

SN - 0749-6524

VL - 12

SP - 551

EP - 556

JO - Infections in Medicine

JF - Infections in Medicine

IS - 10

ER -

Oral ofloxacin versus cefaclor for LRTIs in adults

Abstract

Keywords

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