Oral contraceptives and the risk of multiple sclerosis: A review of the epidemiologic evidence

Alvaro Alonso, Cari Jo Clark

Research output: Contribution to journalArticlepeer-review

39 Scopus citations

Abstract

Multiple sclerosis (MS) is more frequent in women than in men, suggesting that sex hormones could play a role in the development of MS. For this reason, several studies have assessed whether use of oral contraceptives modifies the risk of MS. In this article, we review the methodology and results of published epidemiologic studies addressing this issue. On the whole, the existing epidemiologic evidence does not support an important effect of oral contraceptive use on the risk of MS, though it does suggest that oral contraceptives might delay the onset of the disease.

Original languageEnglish (US)
Pages (from-to)73-75
Number of pages3
JournalJournal of the Neurological Sciences
Volume286
Issue number1-2
DOIs
StatePublished - Nov 15 2009

Keywords

  • Epidemiology
  • Estrogens
  • Multiple sclerosis
  • Oral contraceptive

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