Oral Administration of (S)-Allyl- l -Cysteine and Aged Garlic Extract to Rats: Determination of Metabolites and Their Pharmacokinetics

Keyphrases

• Pharmacokinetics 100%
• Oral Administration 100%
• S-allyl Cysteine 100%
• Aged Garlic Extract 100%
• N-acetylation 38%
• Cysteine Sulfoxides 28%
• Liquid Chromatography-tandem Mass Spectrometry (LC-MS/MS) 9%
• Rat Plasma 9%
• MS Method 9%
• Pharmacokinetic Study 4%
• Plasma Samples 4%
• Bioactive Compounds 4%
• Mass Spectrometer 4%
• Garlic 4%
• Mobile Phase 4%
• Limit of Quantification 4%
• Regulatory Requirements 4%
• Concentration Level 4%
• Acetonitrile 4%
• Chromatographic Separation 4%
• Reversed Phase 4%
• Formic Acid 4%
• Calibration Curve 4%
• Simultaneous Quantification 4%
• Multiple Reaction Monitoring 4%
• Matrix Effect 4%
• Matrix Recovery 4%
• Atmospheric Pressure Ionization 4%
• C-18 4%
• Matrix Stability 4%

Pharmacology, Toxicology and Pharmaceutical Science

• Cysteine 100%
• Allyl 100%
• Garlic Extract 100%
• Pharmacokinetics 100%
• Oral Administration 100%
• Acetic Acid Derivative 38%
• Sulfoxide 28%
• Formate 4%
• Allium sativum 4%
• Acetonitrile 4%