OPTN/SRTR 2017 Annual Data Report: Liver

W. R. Kim, J. R. Lake, J. M. Smith, D. P. Schladt, M. A. Skeans, S. M. Noreen, A. M. Robinson, E. Miller, J. J. Snyder, A. K. Israni, B. L. Kasiske

Research output: Contribution to journalArticlepeer-review

250 Scopus citations


Data on adult liver transplants performed in the US in 2017 are notable for (1) continued growth in numbers of new waitlist registrants (11,514) and of transplants performed (8,082); (2) continued increase in the transplant rate (51.5 per 100 waitlist-years); (3) a precipitous decrease in waitlist registrations and transplants for hepatitis C-related indications; (4) reciprocal increases in waitlist registrants and recipients with alcoholic liver disease and with clinical profiles consistent with non-alcoholic fatty liver disease; and (5) continued improvement in graft survival despite changing recipient characteristics such as older age and higher rates of obesity. Variability in transplant rates remained by candidate race, presence of hepatocellular carcinoma, urgency status (status 1A versus model for end-stage liver disease (MELD) score >35), and geography. More than half of all children listed for liver transplant in 2017 were aged younger than 5 years in 2017, and the highest rate of pretransplant mortality persisted for children aged younger than 1 year. Children underwent transplant at higher acuity than the past, as evidenced by higher MELD/pediatric endstage liver disease scores and listings at status 1A and 1B. Higher acuity at transplant is likely due to lack of access to suitable donor organs, which has been compensated for by persistent trends toward use of partial or split liver grafts and ABO-incompatible grafts. Despite higher illness severity scores at transplant, pediatric graft and patient survival posttransplant have improved over time.

Original languageEnglish (US)
Pages (from-to)184-283
Number of pages100
JournalAmerican Journal of Transplantation
StatePublished - 2019

Bibliographical note

Publisher Copyright:
© 2019, John Wiley and Sons Inc. All rights reserved.


  • Liver transplant
  • allocation
  • distribution
  • waiting list

PubMed: MeSH publication types

  • Research Support, Non-U.S. Gov't
  • Research Support, U.S. Gov't, P.H.S.
  • Journal Article


Dive into the research topics of 'OPTN/SRTR 2017 Annual Data Report: Liver'. Together they form a unique fingerprint.

Cite this