Optimizing cancer care for hepatocellular carcinoma at a safety-net hospital: The value of a multidisciplinary disease management team

Grace Duininck, Alexandra G. Lopez-Aguiar, Rachel M. Lee, Lesley Miller, Sean Dariushnia, Christina Wu, Olatunji B. Alese, Jolinta Y. Lin, Joel Wedd, Andrew Adams, Shishir K. Maithel, Maria C. Russell

Research output: Contribution to journalArticlepeer-review

8 Scopus citations

Abstract

Background: Hepatitis C (HCV) is the primary etiology of hepatocellular carcinoma (HCC) in the US multidisciplinary disease management teams (DMT) that optimize oncologic care. The impact of DMT for HCC in safety-net hospitals is unknown. Methods: Patients diagnosed with HCC from 2009 to 2016 at Grady Memorial Hospital (GMH) were included. The primary aim was to evaluate referrals to care, receipt of therapy, and overall survival (OS) after DMT formation. Screening patterns of HCV patients for HCC were also examined. Results: Of 204 HCC patients, median age was 58 years, with 81% male, 83% black. 46% presented with stage 4 disease, 53% had treatment with median OS 9.8 months. DMT formation was associated with increased referrals to surgery (49% vs 30%; P =.02), liver-directed therapy (58% vs 31%; P =.001), and radiation (13% vs 3%; P =.019). Patients were also more likely to get treatment (59% vs 41%; P =.026), with improved median OS (30.7 vs 4.9 months; P <.001). DMT did not alter HCV screening for HCC (23%). HCV patients screened for HCC had earlier stage disease (P =.001). Conclusion: Implementation of a DMT at GMH is associated with increased HCC patients referred for/receiving treatment, as well as improved survival. Few patients with HCV at risk for HCC are screened, despite DMT. Future efforts should aim to establish screening programs for HCV patients at risk for HCC.

Original languageEnglish (US)
Pages (from-to)1365-1370
Number of pages6
JournalJournal of Surgical Oncology
Volume120
Issue number8
DOIs
StatePublished - Dec 1 2019
Externally publishedYes

Keywords

  • disease management team
  • hepatocellular carcinoma
  • safety-net hospital

PubMed: MeSH publication types

  • Comparative Study
  • Journal Article

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