Optimization of magnetic anisotropy and applied fields for hyperthermia applications

Magnetic anisotropy and applied fields for hyperthermia applications have been optimized for iron cobalt nanocrystalline particles using numerical micromagnetics. The optimized anisotropy energy is [formula omitted] at 500 KHz and the hysteresis loss at this optimized energy is approximately [formula omitted] for a very small oscillating field of magnitude 10 Oe. We have also investigated the effects of varying the applied field and find that the addition of a 20 Oe static field applied perpendicular to the oscillating field approximately doubles the energy loss without subjecting the patient to additional radiation. This is an important benefit for magnetic hyperthermia.