Optic neuropathy in vitamin B12 deficiency

Sai H. Chavala, Gregory S. Kosmorsky, Mina K. Lee, Michael S. Lee

Research output: Contribution to journalArticlepeer-review

26 Scopus citations


There are many neurological manifestations of vitamin B12 deficiency. Optic neuropathy is a rare, but important, manifestation of vitamin B12 deficiency that should be suspected in patients with risk factors for malnutrition. We present a case of a 68-year-old male who presented with bilateral decreased central vision for months and was found to have a low vitamin B12 level. After a few months, his vision improved with parenteral vitamin B12 supplementation. Vitamin B12 optic neuropathy is a reversible, treatable cause of vision loss and may be a harbinger for other manifestations of the disease.

Original languageEnglish (US)
Pages (from-to)447-448
Number of pages2
JournalEuropean Journal of Internal Medicine
Issue number6
StatePublished - Oct 2005

Bibliographical note

Copyright 2008 Elsevier B.V., All rights reserved.


  • Cobalamin
  • Optic neuropathy
  • Tobacco
  • Vision loss


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