Opportunities and challenges for immunosuppression in the context of pig-to-human xenotransplantation

Guillaume Onyeaghala; Casey R. Dorr; Ajay K. Israni

doi:10.1016/j.medj.2024.07.017

Opportunities and challenges for immunosuppression in the context of pig-to-human xenotransplantation

Guillaume Onyeaghala
, Casey R. Dorr
, Ajay K. Israni

Medicine - Renal and Hypertension Division

Research output: Contribution to journal › Comment/debate › peer-review

1 Scopus citations

Abstract

The transplantation of organ(s) across species may alleviate the shortage of available donor kidneys for an ever-growing number of patients on transplant waiting lists. However, this potential remains limited by uncharacterized physiologic and immune effects of xenotransplants in recipients, which Pan et al.¹ investigated in the current study.

Original language	English (US)
Pages (from-to)	842-844
Number of pages	3
Journal	Med
Volume	5
Issue number	8
DOIs	https://doi.org/10.1016/j.medj.2024.07.017
State	Published - Aug 9 2024

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title = "Opportunities and challenges for immunosuppression in the context of pig-to-human xenotransplantation",

abstract = "The transplantation of organ(s) across species may alleviate the shortage of available donor kidneys for an ever-growing number of patients on transplant waiting lists. However, this potential remains limited by uncharacterized physiologic and immune effects of xenotransplants in recipients, which Pan et al.1 investigated in the current study.",

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AU - Dorr, Casey R.

AU - Israni, Ajay K.

PY - 2024/8/9

Y1 - 2024/8/9

N2 - The transplantation of organ(s) across species may alleviate the shortage of available donor kidneys for an ever-growing number of patients on transplant waiting lists. However, this potential remains limited by uncharacterized physiologic and immune effects of xenotransplants in recipients, which Pan et al.1 investigated in the current study.

AB - The transplantation of organ(s) across species may alleviate the shortage of available donor kidneys for an ever-growing number of patients on transplant waiting lists. However, this potential remains limited by uncharacterized physiologic and immune effects of xenotransplants in recipients, which Pan et al.1 investigated in the current study.

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UR - https://www.scopus.com/pages/publications/85200413314#tab=citedBy

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DO - 10.1016/j.medj.2024.07.017

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C2 - 39127030

AN - SCOPUS:85200413314

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Opportunities and challenges for immunosuppression in the context of pig-to-human xenotransplantation

Abstract

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