Opioid peptide effects on feeding in rabbits

Blake A. Gosnell; James M. Lipton

doi:10.1016/0196-9781(86)90089-6

Opioid peptide effects on feeding in rabbits

Blake A. Gosnell
, James M. Lipton

Food Science and Nutrition

Research output: Contribution to journal › Article › peer-review

17 Scopus citations

Abstract

The food intake of rabbits was measured after intracerebroventricular injections of several opioid agonists and naloxone. The preferential kappa agonist dynorphin A increased intake, while naloxone, [D-Ser²,Leu⁵]enkephalin-Thr⁶ and Tyr-D-Ala-Gly-(Me)Phe-Gly-ol reduced intake or had no effect. These results suggest that kappa receptors have a role in the control of feeding in rabbits.

Original language	English (US)
Pages (from-to)	745-747
Number of pages	3
Journal	Peptides
Volume	7
Issue number	5
DOIs	https://doi.org/10.1016/0196-9781(86)90089-6
State	Published - 1986

Keywords

Food intake
Naloxone
Opioids
Rabbits

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10.1016/0196-9781(86)90089-6

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title = "Opioid peptide effects on feeding in rabbits",

abstract = "The food intake of rabbits was measured after intracerebroventricular injections of several opioid agonists and naloxone. The preferential kappa agonist dynorphin A increased intake, while naloxone, [D-Ser2,Leu5]enkephalin-Thr6 and Tyr-D-Ala-Gly-(Me)Phe-Gly-ol reduced intake or had no effect. These results suggest that kappa receptors have a role in the control of feeding in rabbits.",

keywords = "Food intake, Naloxone, Opioids, Rabbits",

author = "Gosnell, \{Blake A.\} and Lipton, \{James M.\}",

year = "1986",

doi = "10.1016/0196-9781(86)90089-6",

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volume = "7",

pages = "745--747",

journal = "Peptides",

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TY - JOUR

T1 - Opioid peptide effects on feeding in rabbits

AU - Gosnell, Blake A.

AU - Lipton, James M.

PY - 1986

Y1 - 1986

N2 - The food intake of rabbits was measured after intracerebroventricular injections of several opioid agonists and naloxone. The preferential kappa agonist dynorphin A increased intake, while naloxone, [D-Ser2,Leu5]enkephalin-Thr6 and Tyr-D-Ala-Gly-(Me)Phe-Gly-ol reduced intake or had no effect. These results suggest that kappa receptors have a role in the control of feeding in rabbits.

AB - The food intake of rabbits was measured after intracerebroventricular injections of several opioid agonists and naloxone. The preferential kappa agonist dynorphin A increased intake, while naloxone, [D-Ser2,Leu5]enkephalin-Thr6 and Tyr-D-Ala-Gly-(Me)Phe-Gly-ol reduced intake or had no effect. These results suggest that kappa receptors have a role in the control of feeding in rabbits.

KW - Food intake

KW - Naloxone

KW - Opioids

KW - Rabbits

UR - https://www.scopus.com/pages/publications/0023005894

UR - https://www.scopus.com/pages/publications/0023005894#tab=citedBy

U2 - 10.1016/0196-9781(86)90089-6

DO - 10.1016/0196-9781(86)90089-6

M3 - Article

C2 - 3797341

AN - SCOPUS:0023005894

SN - 0196-9781

VL - 7

SP - 745

EP - 747

JO - Peptides

JF - Peptides

IS - 5

ER -

Opioid peptide effects on feeding in rabbits

Abstract

Keywords

Publisher link

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