Opioid peptide effects on feeding in rabbits

Blake A. Gosnell, James M. Lipton

Research output: Contribution to journalArticle

15 Scopus citations

Abstract

The food intake of rabbits was measured after intracerebroventricular injections of several opioid agonists and naloxone. The preferential kappa agonist dynorphin A increased intake, while naloxone, [D-Ser2,Leu5]enkephalin-Thr6 and Tyr-D-Ala-Gly-(Me)Phe-Gly-ol reduced intake or had no effect. These results suggest that kappa receptors have a role in the control of feeding in rabbits.

Original languageEnglish (US)
Pages (from-to)745-747
Number of pages3
JournalPeptides
Volume7
Issue number5
DOIs
StatePublished - Jan 1 1986

Keywords

  • Food intake
  • Naloxone
  • Opioids
  • Rabbits

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