TY - JOUR
T1 - Opioid-binding cell adhesion molecule (OBCAM)-related clones from a rat brain cDNA library
AU - Lippman, David A.
AU - Lee, Nancy M.
AU - Loh, Horace H
PY - 1992/8/15
Y1 - 1992/8/15
N2 - A rat brain cDNA library was screened with probes constructed from portions of the cDNA (OBCAM) encoding the opioid-binding cell adhesion molecule (OBCAM). Three clones of interest were isolated and sequenced. The largest clone, DUZ1, had a putative open reading frame (ORF) essentially identical to OBCAM in its C-terminal 318 amino acids (aa), but differing in its N-terminal aa (20 vs. 27 in OBCAM), and in all of its 5′-noncoding regions. The other clones, SG8 and SG13, had a putative ORF essentially identical to that of OBCAM, but differed from each other in a portion of their 5′-noncoding region. This study suggests that there is a family of OBCAM-like genes.
AB - A rat brain cDNA library was screened with probes constructed from portions of the cDNA (OBCAM) encoding the opioid-binding cell adhesion molecule (OBCAM). Three clones of interest were isolated and sequenced. The largest clone, DUZ1, had a putative open reading frame (ORF) essentially identical to OBCAM in its C-terminal 318 amino acids (aa), but differing in its N-terminal aa (20 vs. 27 in OBCAM), and in all of its 5′-noncoding regions. The other clones, SG8 and SG13, had a putative ORF essentially identical to that of OBCAM, but differed from each other in a portion of their 5′-noncoding region. This study suggests that there is a family of OBCAM-like genes.
KW - Opioid receptor
KW - cDNA cloning
KW - cell adhesion molecules
KW - immunoglobulin superfamily
UR - http://www.scopus.com/inward/record.url?scp=0026750474&partnerID=8YFLogxK
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U2 - 10.1016/0378-1119(92)90734-7
DO - 10.1016/0378-1119(92)90734-7
M3 - Article
C2 - 1339369
AN - SCOPUS:0026750474
VL - 117
SP - 249
EP - 254
JO - Gene
JF - Gene
SN - 0378-1119
IS - 2
ER -