Operative technique and atrial tachyarrhythmias after orthotopic heart transplantation

Srinivasan Sattiraju, Shashank Vats, Balaji Krishnan, Sun K. Kim, Erin Austin, Ilknur Can, Venkatakrishna Tholakanahalli, David G. Benditt, Lin Y. Chen

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Abstract

There is conflicting evidence that operative technique affects the risk of atrial tachyarrhythmia after orthotopic heart transplantation (OHT). We sought to determine whether OHT by bicaval (BC) technique is associated with a lower risk of atrial tachyarrhythmia than biatrial (BA) technique. Consecutive patients who underwent OHT between 1997 and 2007 at the University of Minnesota were included in this retrospective cohort study with follow-up through December 31, 2011. We included 260 OHT recipients (BA, 155; BC, 105). Fifty-nine patients (22.7%) developed early atrial tachyarrhythmias. The multivariable odds ratio (95% confidence interval [CI]) of BC technique for early atrial tachyarrhythmias was 0.85 (0.46-1.57), P=0.59. After a median follow-up of 4.9 years, 40 (15.4%) patients developed late atrial tachyarrhythmias. The multivariable hazard ratio (HR) (95% CI) of BC technique for late atrial tachyarrhythmias was 0.99 (0.50-1.96), P=0.98. Graft rejection was found to be a multivariate predictor of late atrial tachyarrhythmias (HR, 2.89; 95% CI, 1.48-5.65; P=0.002). In contrast to prior reports, we did not find an association between operative technique and early or late atrial tachyarrhythmias after OHT. Graft rejection is a risk factor for late atrial tachyarrhythmias after OHT.

Original languageEnglish (US)
Pages (from-to)31-38
Number of pages8
JournalJournal of Atrial Fibrillation
Volume5
Issue number4
StatePublished - Dec 1 2012

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Heart Transplantation
Tachycardia
Graft Rejection
Confidence Intervals
Cohort Studies
Retrospective Studies
Odds Ratio

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Operative technique and atrial tachyarrhythmias after orthotopic heart transplantation. / Sattiraju, Srinivasan; Vats, Shashank; Krishnan, Balaji; Kim, Sun K.; Austin, Erin; Can, Ilknur; Tholakanahalli, Venkatakrishna; Benditt, David G.; Chen, Lin Y.

In: Journal of Atrial Fibrillation, Vol. 5, No. 4, 01.12.2012, p. 31-38.

Research output: Contribution to journalArticle

Sattiraju S, Vats S, Krishnan B, Kim SK, Austin E, Can I et al. Operative technique and atrial tachyarrhythmias after orthotopic heart transplantation. Journal of Atrial Fibrillation. 2012 Dec 1;5(4):31-38.
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