One-step facile synthesis of deuterium labeled aldehydes from tertiary amides using Cp2Zr(D)Cl

Jared T. Spletstoser, Jonathan M. White, Gunda I. Georg

Research output: Contribution to journalArticle

33 Scopus citations

Abstract

The synthesis of deuterium labeled aldehydes was accomplished in an expedient and facile manner through the reduction of amides using commercially available Cp2Zr(D)Cl. The reactions proceeded rapidly (ca. 15min) and in high yields (70-99%).

Original languageEnglish (US)
Pages (from-to)2787-2789
Number of pages3
JournalTetrahedron Letters
Volume45
Issue number13
DOIs
StatePublished - Mar 22 2004

Keywords

  • Amide
  • CpZr(D)Cl
  • Deuterium labeled aldehyde
  • Reduction
  • Schwartz reagent
  • Zirconium

Fingerprint Dive into the research topics of 'One-step facile synthesis of deuterium labeled aldehydes from tertiary amides using Cp<sub>2</sub>Zr(D)Cl'. Together they form a unique fingerprint.

  • Cite this