Oncologic management of sinonasal undifferentiated carcinoma

Matthew A. Tyler, Brittany Holmes, Zara M. Patel

Research output: Contribution to journalReview articlepeer-review

14 Scopus citations


Purpose of reviewThis article reviews the latest treatment paradigms in sinonasal undifferentiated carcinoma (SNUC).Recent findingsThe aggressive biology and associated advanced presentation of SNUC make successful treatment a challenge shared across medical specialties. Still, studies reporting outcomes in SNUC indicate that an aggressive treatment strategy consisting of surgery, radiation and chemotherapy offers the best chance of prolonged survival.SummarySuccessful treatment of SNUC requires highly specialized care at tertiary cancer treatment facilities. A better understanding of the biology of the disease coupled with increasing outcome reporting will lead to optimized treatment regimens.

Original languageEnglish (US)
Pages (from-to)59-66
Number of pages8
JournalCurrent Opinion in Otolaryngology and Head and Neck Surgery
Issue number1
StatePublished - Feb 1 2019
Externally publishedYes

Bibliographical note

Publisher Copyright:
© 2018 Wolters Kluwer Health, Inc. All rights reserved.


  • sinonasal cancer
  • sinonasal tumors
  • sinonasal undifferentiated carcinoma
  • sinus tumors
  • skull base cancer
  • skull base surgery


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