Abstract
As improved therapy prolongs the lives of cancer patients, the prevalence of oncologic emergencies continues to increase. However, nonspecific clinical features misattributed to the underlying cancer complicate their diagnosis. In this chapter, we review febrile neutropenia, metastatic spinal cord compression (MSCC), malignant pericardial disease, hypercalcemia of malignancy, tumor lysis syndrome (TLS), leukostasis, superior vena cava (SVC) syndrome, and complications of cancer immunotherapies such as monoclonal antibodies, T-lymphocyte checkpoint inhibition, and adoptive cell transfer therapy.
| Original language | English (US) |
|---|---|
| Title of host publication | Rosen's Emergency Medicine |
| Subtitle of host publication | Concepts and Clinical Practice: 2-Volume Set |
| Publisher | Elsevier |
| Pages | 1500-1516.e4 |
| ISBN (Electronic) | 9780323757898 |
| ISBN (Print) | 9780323757904 |
| DOIs | |
| State | Published - Jan 1 2022 |
Bibliographical note
Publisher Copyright:© 2023 Elsevier Inc. All rights reserved.
Keywords
- CAR T-cell therapy
- Febrile neutropenia
- Metastatic spinal cord compression
- Monoclonal antibody therapy
- Oncologic emergencies
- T-cell checkpoint inhibitor therapy
- Tumor lysis syndrome