Chemical examination of the soft coral Sinularia granosa collected from the Havelock island of the Indian Ocean furnishes four highly oxygenated novel diterpenoids 1 to 4 along with a polyhydroxysterol, 24-methylenecholestane - 1α, 5α, 6β, 11α-pentol 5. One of the diterpenoids, 4, designated as havellockate, possesses a seco and rearranged cembranoid skeleton whose structure has been established by complete spectral analysis including X-ray data. A possible biogenetic sequence has been suggested for the polyoxygenated cembranoids 1-4 and 6.
|Original language||English (US)|
|Number of pages||6|
|Journal||Indian Journal of Chemistry - Section B Organic and Medicinal Chemistry|
|State||Published - Jan 1 2000|