On the mechanism of reduced tabletability of granules prepared by roller compaction

Changquan Calvin Sun

doi:10.1016/j.ijpharm.2007.10.002

On the mechanism of reduced tabletability of granules prepared by roller compaction

Changquan Calvin Sun

Pharmaceutics

Research output: Contribution to journal › Letter › peer-review

27 Scopus citations

Abstract

In a recent paper published in this journal, authors were perplexed by their results seemingly conflicting with our earlier findings [Sun, C.C., Himmelspach, M.W., 2006. Reduced tabletability of roller compacted granules as a result of granule size enlargement. J. Pharm. Sci. 95, 200-206]. After carefully reviewing the two studies, we conclude that results in the two studies are actually consistent with each other.

Original language	English (US)
Pages (from-to)	171-172
Number of pages	2
Journal	International journal of pharmaceutics
Volume	347
Issue number	1-2
DOIs	https://doi.org/10.1016/j.ijpharm.2007.10.002
State	Published - Jan 22 2008

Keywords

Dry granulation
Granule size
Powder compaction
Roller compaction
Tabletability

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10.1016/j.ijpharm.2007.10.002

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AB - In a recent paper published in this journal, authors were perplexed by their results seemingly conflicting with our earlier findings [Sun, C.C., Himmelspach, M.W., 2006. Reduced tabletability of roller compacted granules as a result of granule size enlargement. J. Pharm. Sci. 95, 200-206]. After carefully reviewing the two studies, we conclude that results in the two studies are actually consistent with each other.

KW - Dry granulation

KW - Granule size

KW - Powder compaction

KW - Roller compaction

KW - Tabletability

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ER -

On the mechanism of reduced tabletability of granules prepared by roller compaction

Abstract

Keywords

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