The effects of gymnemic acid, 1 mg/ml, and miraculin, 1 mg/ml or in a tablet (Miralin™) on the taste response to sucrose, citric acid, NaCl and quinine have been studied in dog, pig and rabbit. In the dog gymnemic acid suppressed the response to sucrose for about 5 min in two out of three animals. It also affected the response to NaCl. Miraculin caused a slight short-lasting increase in the response to acid. No effects of the taste modifiers were observed in the pig. In the rabbit gymnemic acid did not suppress the response to sucrose while miraculin enhanced the response to citric acid in one out of three animals for a few minutes.
Bibliographical noteFunding Information:
The author is indebted to Dr H. van der Wei and J. N. Brouwer, Unilever Research, Vlaardingen, Netherlands, who supplied the gymnemic acid and miraculin used. This study was supported by grants fromMaltdrycksforsknigsradet.Knut och Alice Wallenbergs Stiftelse, Magnus Bergvalls Stiftelse and the Swedish Medical Research Council grant No.2467.