On the Effects of Gymnemic Acid in the Hamster and Rat

Göran Hellekant, V. Gopal

Research output: Contribution to journalArticlepeer-review

25 Scopus citations

Abstract

The gustatory activity of the chorda tympani proper nerve has been recorded before and after the application of gymnemic acid to the tongue of hamster and rat. Concentrations of pure gymnemic acid ranging from 1 mg/ml to 10 mg/ml have been used. In the hamster gymnemic acid suppressed the response to solutions of sucrose especially, but it also caused, at higher concentrations, a general suppression of the taste response. The depression caused in the response to sucrose was directly related to the strength of the gymnemic acid and inversely to that of the sucrose solution. In the rat a suppression of the response to saccharin was obtained but no suppression of the taste response to sucrose by gymnemic acid was observed.

Original languageEnglish (US)
Pages (from-to)136-142
Number of pages7
JournalActa Physiologica Scandinavica
Volume98
Issue number2
DOIs
StatePublished - Oct 1976

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