On-line biomass estimation using a modified oxygen utilization rate

S. B. Petkov, R. A. Davis

Research output: Contribution to journalArticle

8 Citations (Scopus)

Abstract

A procedure for estimating biomass during batch fermentation from on-line gas analysis is presented. First, the respiratory quotient was used to determine the fraction of the total oxygen utilization rate required for cell maintenance and growth versus product synthesis. The modified oxygen utilization rate was then used to estimate biomass on-line by integrating the oxygen balance for cell synthesis-maintenance. The method is illustrated for the case of L-lysine synthesis by Corynebacterium glutamicum.

Original languageEnglish (US)
Pages (from-to)43-45
Number of pages3
JournalBioprocess and Biosystems Engineering
Volume15
Issue number1
DOIs
StatePublished - Jan 1 1996

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Biomass
Oxygen
Maintenance
Corynebacterium glutamicum
Gas fuel analysis
Fermentation
Lysine
Gases
Growth

Cite this

On-line biomass estimation using a modified oxygen utilization rate. / Petkov, S. B.; Davis, R. A.

In: Bioprocess and Biosystems Engineering, Vol. 15, No. 1, 01.01.1996, p. 43-45.

Research output: Contribution to journalArticle

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