Octanol-water partition coefficients of cyclic C-7 hydrocarbons and selected derivatives

Keith B Lodge

Research output: Contribution to journalArticle

12 Citations (Scopus)

Abstract

Partition coefficients between 1-octanol and water, Kow, of 16 C-7 cyclic hydrocarbons were measured using the classic shake-flask method or the more recent slow-stir method. For eight compounds, both methods were used and the results are summarized by log Kow(shake flask) = m log Kow(slow stir), where m is 0.998 ± 0.003 (±SD). The compounds include quadricyclane, bicyclohepta-2,5-diene, norbornylene, norborane, and commercially available derivatives containing oxygen or halogen atoms. The rapid hydrolysis of three halogenated derivatives prevented direct measurements; estimates for these were calculated from retention times measured with a C-18 reverse-phase column. The compounds are hydrophilic to moderately hydrophobic; the values of log Kow range from -0.42 to 3.78.

Original languageEnglish (US)
Pages (from-to)1321-1324
Number of pages4
JournalJournal of Chemical and Engineering Data
Volume44
Issue number6
DOIs
StatePublished - Nov 1 1999

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Octanols
Hydrocarbons
Cyclic Hydrocarbons
1-Octanol
Derivatives
Halogens
Water
Hydrolysis
Oxygen
Atoms
quadricyclane
2-norbornene

Cite this

Octanol-water partition coefficients of cyclic C-7 hydrocarbons and selected derivatives. / Lodge, Keith B.

In: Journal of Chemical and Engineering Data, Vol. 44, No. 6, 01.11.1999, p. 1321-1324.

Research output: Contribution to journalArticle

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