Objective outcome measures: Collecting meaningful data on alopecia areata

Elise A. Olsen, Janet Roberts, Leonard Sperling, Antonella Tosti, Jerry Shapiro, Amy McMichael, Wilma Bergfeld, Valerie Callender, Paradi Mirmirani, Ken Washenik, David Whiting, George Cotsarelis, Maria Hordinsky

Research output: Contribution to journalArticlepeer-review

41 Scopus citations


Background: Although alopecia areata is a common disorder, it has no US Food and Drug Administration–approved treatment and evidence-based therapeutic data are lacking. Objective: To develop guidelines for the diagnosis, evaluation, assessment, response criteria, and end points for alopecia areata. Methods: Literature review and expert opinion of a group of dermatologists specializing in hair disorders. Results: Standardized methods of assessing and tracking hair loss and growth, including new scoring techniques, response criteria, and end points in alopecia areata are presented. Limitations: The additional time to perform the assessments is the primary limitation to use of the methodology in clinical practice. Conclusion: Use of these measures will facilitate collection of standardized outcome data on therapeutic agents used in alopecia areata both in clinical practice and in clinical trials.

Original languageEnglish (US)
Pages (from-to)470-478.e3
JournalJournal of the American Academy of Dermatology
Issue number3
StatePublished - Sep 2018

Bibliographical note

Funding Information:
Supported in part by the Duke University Hair Disorders Research and Treatment Center and the Leirion Foundation.

Publisher Copyright:
© 2017 American Academy of Dermatology, Inc.


  • ALODEX score
  • SALT score
  • alopecia areata
  • assessment measures
  • outcome measures
  • response criteria


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