Obesity in liver transplantation: A risk factor for unplanned reoperation and prolonged operative time

James S. Ford, Eric S. Wise, Saad C. Rehman, Kristina Gloria Jacomino, Michael J. Maggart, Michelle Izmaylov, Sunil K. Geevarghese

Research output: Contribution to journalArticlepeer-review

Abstract

Selection of orthotopic liver transplantation (OLT) candidates is increasingly inclusive of patients with high BMI. We aim to characterize the influence of obesity on the surgical outcome measures of prolonged operative time and unplanned reoperation. We reviewed the records of obese and normal weight OLT recipients over a 10-year period from a single institution. Variables that trended (P < 0.1) with endpoints on univariate analysis were put into multivariate logistic regression models to determine independent association (P < 0.05). We included 195 obese and 171 normal weight OLT recipients in our study. On multivariate analysis, obesity was the only preoperative risk factor that trended with unplanned reoperation (odds ratio 2, P 5 0.05). Similarly, only obesity remained independently associated with prolonged length of operation (defined as ‡275 minutes) on multivariate analysis (odds ratio 1.7, P 5 0.04). In summary, obesity may make OLT more technically challenging and, thus, represents an independent risk factor for unplanned reoperations and prolonged operative time.

Original languageEnglish (US)
Pages (from-to)927-933
Number of pages7
JournalAmerican Surgeon
Volume85
Issue number8
StatePublished - Jan 1 2019
Externally publishedYes

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