Obesity and breast cancer: A clinical biochemistry perspective

Amitabha Ray, Margot P Cleary

Research output: Contribution to journalReview article

27 Scopus citations

Abstract

Objectives: To evaluate the laboratory diagnosis aspects of obesity-related health problems with special reference to postmenopausal breast cancer. Design and methods: We conducted a systemic search of the literature primarily from the PubMed to obtain the relevant data. Results: Obesity is associated with the dysregulations of a number of body components such as blood constituents, extracellular matrix, and hormones/growth factors axes, which could be utilized for early diagnosis. Conclusions: Obesity-related disorders including breast cancer have emerged as major health problems in almost all the nations. There is a need to elucidate different biochemical markers that are being used in the clinics or have the potential for such use. A precise understanding of the complex pathologies related with obesity is useful in prevention, early diagnosis and overall clinical management.

Original languageEnglish (US)
Pages (from-to)189-197
Number of pages9
JournalClinical Biochemistry
Volume45
Issue number3
DOIs
StatePublished - Feb 1 2012

Keywords

  • Adiposity
  • Lab-diagnosis
  • Leptin
  • Lipids
  • Neoplasia

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