TY - JOUR
T1 - Obesity among HIV-infected persons
T2 - Impact of weight on CD4 cell count
AU - Crum-Cianflone, Nancy F.
AU - Roediger, Mollie
AU - Eberly, Lynn E.
AU - Vyas, Kurt
AU - Landrum, Mike L.
AU - Ganesan, Anuradha
AU - Weintrob, Amy C.
AU - Barthel, Robert Vincent
AU - Agan, Brian K.
PY - 2010/4
Y1 - 2010/4
N2 - To assess the effect of obesity on CD4 cell counts, we estimated the association of time-updated BMI categories with CD4 changes among 1001 documented HIV seroconverters. During the pre-highly active antiretroviral therapy (HAART) era, a higher BMI was associated with less reduction in CD4 cell counts over time. However during the HAART era, obese versus normal weight patients had smaller increases in CD4 cell counts (+69 versus +116 cells, P = 0.01). Lower CD4 cell counts may now be another adverse consequence of obesity.
AB - To assess the effect of obesity on CD4 cell counts, we estimated the association of time-updated BMI categories with CD4 changes among 1001 documented HIV seroconverters. During the pre-highly active antiretroviral therapy (HAART) era, a higher BMI was associated with less reduction in CD4 cell counts over time. However during the HAART era, obese versus normal weight patients had smaller increases in CD4 cell counts (+69 versus +116 cells, P = 0.01). Lower CD4 cell counts may now be another adverse consequence of obesity.
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U2 - 10.1097/QAD.0b013e328337fe01
DO - 10.1097/QAD.0b013e328337fe01
M3 - Article
C2 - 20216300
AN - SCOPUS:77950957316
SN - 0269-9370
VL - 24
SP - 1069
EP - 1072
JO - AIDS
JF - AIDS
IS - 7
ER -
