Nutrients and the pancreas: An epigenetic perspective

Andee Weisbeck, Rick J. Jansen

Research output: Contribution to journalReview articlepeer-review

25 Scopus citations

Abstract

Pancreatic cancer is the fourth most common cause of cancer-related deaths with a dismal average five-year survival rate of six percent. Substitutional progress has been made in understanding how pancreatic cancer develops and progresses. Evidence is mounting which demonstrates that diet and nutrition are key factors in carcinogenesis. In particular, diets low in folate and high in fruits, vegetables, red/processed meat, and saturated fat have been identified as pancreatic cancer risk factors with a proposed mechanism involving epigenetic modifications or gene regulation. We review the current literature assessing the correlation between diet, epigenetics, and pancreatic cancer.

Original languageEnglish (US)
Article number283
JournalNutrients
Volume9
Issue number3
DOIs
StatePublished - Mar 15 2017
Externally publishedYes

Bibliographical note

Funding Information:
This project was supported using research funds provided by North Dakota State University.

Publisher Copyright:
© 2017 by the authors. Licensee MDPI, Basel, Switzerland.

Keywords

  • Epigenetics
  • Nutrition
  • Pancreatic cancer

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