Nuclear magnetic resonance spectroscopy. Concentration dependence of the T1 relaxation time for 13C in dioxane-D2O. Some experimental problems with T1 measurements

Ian M. Armitage; Hanspeter Huber; David H. Live; H. Pearson; John D. Roberts

doi:10.1016/0022-2364(74)90183-8

Nuclear magnetic resonance spectroscopy. Concentration dependence of the T₁ relaxation time for ¹³C in dioxane-D₂O. Some experimental problems with T₁ measurements

Ian M. Armitage, Hanspeter Huber, David H. Live, H. Pearson, John D. Roberts

Biochemistry, Molecular Biology, and Biophysics (TMED)

Research output: Contribution to journal › Article › peer-review

25 Scopus citations

Abstract

The ¹³C T₁ relaxation times determined for dioxane-D₂O solutions by the progressive saturation method have been found to range from 5 sec for 1:1 (v/v) dioxane-D₂O to 12 sec for neat dioxane. The concentration dependence roughly parallels the inverse of the viscosity and is likely to be associated with changes in correlation times because of hydrogen bonding. A 2:1 (v/v) dioxane-D₂O mixture with a T₁ of 6.2 ± 0.6 sec at 30°C has been found to be a useful standard for checking instrument performance in the determination of T₁ values. A number of experimental problems associated with measuring T₁ are discussed.

Original language	English (US)
Pages (from-to)	142-149
Number of pages	8
Journal	Journal of Magnetic Resonance (1969)
Volume	15
Issue number	1
DOIs	https://doi.org/10.1016/0022-2364(74)90183-8
State	Published - Jul 1974

Bibliographical note

Funding Information:
* Supported by the Public Health Service, Research Grant No. GM-1 1072, from the Division of General Medical Sciences. t Contribution No. 4840. : Harkness Fellow, 1972-1974.

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Nuclear magnetic resonance spectroscopy. Concentration dependence of the T₁ relaxation time for ¹³C in dioxane-D₂O. Some experimental problems with T₁ measurements. / Armitage, Ian M.; Huber, Hanspeter; Live, David H. et al.

In: Journal of Magnetic Resonance (1969), Vol. 15, No. 1, 07.1974, p. 142-149.

Research output: Contribution to journal › Article › peer-review

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title = "Nuclear magnetic resonance spectroscopy. Concentration dependence of the T1 relaxation time for 13C in dioxane-D2O. Some experimental problems with T1 measurements",

abstract = "The 13C T1 relaxation times determined for dioxane-D2O solutions by the progressive saturation method have been found to range from 5 sec for 1:1 (v/v) dioxane-D2O to 12 sec for neat dioxane. The concentration dependence roughly parallels the inverse of the viscosity and is likely to be associated with changes in correlation times because of hydrogen bonding. A 2:1 (v/v) dioxane-D2O mixture with a T1 of 6.2 ± 0.6 sec at 30°C has been found to be a useful standard for checking instrument performance in the determination of T1 values. A number of experimental problems associated with measuring T1 are discussed.",

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note = "Funding Information: * Supported by the Public Health Service, Research Grant No. GM-1 1072, from the Division of General Medical Sciences. t Contribution No. 4840. : Harkness Fellow, 1972-1974.",

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AU - Armitage, Ian M.

AU - Huber, Hanspeter

AU - Live, David H.

AU - Pearson, H.

AU - Roberts, John D.

N1 - Funding Information: * Supported by the Public Health Service, Research Grant No. GM-1 1072, from the Division of General Medical Sciences. t Contribution No. 4840. : Harkness Fellow, 1972-1974.

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N2 - The 13C T1 relaxation times determined for dioxane-D2O solutions by the progressive saturation method have been found to range from 5 sec for 1:1 (v/v) dioxane-D2O to 12 sec for neat dioxane. The concentration dependence roughly parallels the inverse of the viscosity and is likely to be associated with changes in correlation times because of hydrogen bonding. A 2:1 (v/v) dioxane-D2O mixture with a T1 of 6.2 ± 0.6 sec at 30°C has been found to be a useful standard for checking instrument performance in the determination of T1 values. A number of experimental problems associated with measuring T1 are discussed.

AB - The 13C T1 relaxation times determined for dioxane-D2O solutions by the progressive saturation method have been found to range from 5 sec for 1:1 (v/v) dioxane-D2O to 12 sec for neat dioxane. The concentration dependence roughly parallels the inverse of the viscosity and is likely to be associated with changes in correlation times because of hydrogen bonding. A 2:1 (v/v) dioxane-D2O mixture with a T1 of 6.2 ± 0.6 sec at 30°C has been found to be a useful standard for checking instrument performance in the determination of T1 values. A number of experimental problems associated with measuring T1 are discussed.

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