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Novel, selective CDK9 inhibitors for the treatment of HIV infection
G. Németh
, Z. Varga
, Z. Greff
, G. Bencze
, A. Sipos
, C. Szántai-Kis
, F. Baska
, Á Gyuris
, K. Kelemenics
, Z. Szathmáry
, J. Minárovits
, G. Kéri
, L. Orfi
Chemistry (Twin Cities)
Research output
:
Contribution to journal
›
Article
›
peer-review
34
Scopus citations
Overview
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Keyphrases
Cyclin-dependent Kinase
100%
Treatment of HIV Infection
100%
CDK9 Inhibitor
100%
Cyclin-dependent Kinase 9 (CDK9)
75%
Selective Inhibitor
50%
Inhibitory Activity
50%
Cyclin-dependent Kinase 1 (CDK1)
50%
Gene Expression
25%
Inflammation
25%
HIV Infection
25%
High Selectivity
25%
HIV-1 Replication
25%
Cyclin-dependent Kinase 4 (CDK4)
25%
Cardiac Hypertrophy
25%
Pharmacological Inhibitors
25%
Kinase Assay
25%
Order of Magnitude
25%
IC50
25%
Cytotoxicity Assay
25%
Kinase Family
25%
Derivatization
25%
Synthetic Methods
25%
Inhibitory Profile
25%
Phenylpyrimidine
25%
Cellular Assay
25%
Pharmacology, Toxicology and Pharmaceutical Science
Cyclin Dependent Kinase
100%
Human Immunodeficiency Virus Infection
100%
HIV
25%
Cytotoxicity Assay
25%
Phosphotransferase
25%
Heart Ventricle Hypertrophy
25%
IC50
25%
Inflammation
25%