Novel pharmacological treatments for heart failure

W. H Wilson Tang, Gary S. Francis

Research output: Contribution to journalReview articlepeer-review

11 Scopus citations


Pharmacological therapies remain the primary strategy for treating patients with acute and chronic heart failure. Several novel neurohormonal antagonists, inotropic agents, immune modulators, and metabolic and replacement therapies are currently in development to meet the demands of an increasing number of patients with heart failure. The success in drug development in this field will require a better understanding of the effects of heart failure on drug dosing, better integration of novel and existing drug therapies, the development of more reliable surrogate markers to effectively tailor medical therapy to individual needs and the ability to detect and treat patients at risk before the onset of heart failure.

Original languageEnglish (US)
Pages (from-to)1791-1801
Number of pages11
JournalExpert Opinion on Investigational Drugs
Issue number11
StatePublished - Nov 2003


  • Drug development
  • Heart failure
  • Therapy


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