Novel nickel contact dermatitis in a patient taking isotretinoin

John Conely; Ingrid C Polcari

doi:10.1111/pde.12460

Novel nickel contact dermatitis in a patient taking isotretinoin

John Conely, Ingrid C Polcari

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2 Scopus citations

Abstract

There are many reports about contact dermatitis to nickel and side effects of isotretinoin, but the development of contact dermatitis to a previously tolerated allergen while taking isotretinoin is not well described. We report the case of a 19-year-old man who developed a new nickel allergy during isotretinoin treatment. We theorize that thinning of the stratum corneum by this medication allows for greater antigen presentation and thus sensitization to contact allergens.

Original language	English (US)
Pages (from-to)	e154-e155
Journal	Pediatric Dermatology
Volume	31
Issue number	6
DOIs	https://doi.org/10.1111/pde.12460
State	Published - Nov 1 2014

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© 2014 Wiley Periodicals, Inc.

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abstract = "There are many reports about contact dermatitis to nickel and side effects of isotretinoin, but the development of contact dermatitis to a previously tolerated allergen while taking isotretinoin is not well described. We report the case of a 19-year-old man who developed a new nickel allergy during isotretinoin treatment. We theorize that thinning of the stratum corneum by this medication allows for greater antigen presentation and thus sensitization to contact allergens.",

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AB - There are many reports about contact dermatitis to nickel and side effects of isotretinoin, but the development of contact dermatitis to a previously tolerated allergen while taking isotretinoin is not well described. We report the case of a 19-year-old man who developed a new nickel allergy during isotretinoin treatment. We theorize that thinning of the stratum corneum by this medication allows for greater antigen presentation and thus sensitization to contact allergens.

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Novel nickel contact dermatitis in a patient taking isotretinoin

Abstract

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