Novel fluorescent aminoxy acids and aminoxy hybrid peptides

Alan R. Katritzky, Abdelmotaal Abdelmajeid, Srinivasa R. Tala, M. S. Amine, Peter J. Steel

Research output: Contribution to journalArticlepeer-review

11 Scopus citations


α-Aminoxy acid conjugates and hybrid α-aminoxy dipeptide conjugates showing blue to green fluorescence (with quantum yields 0.23-0.71) were synthesized (75-92% yield) from N-acylbenzotriazoles. 7-Methoxycoumarin derivatives were obtained (quantum yields φ0.35-0.71) that could be suitable for peptide assays. The wavelengths of the absorption maxima (λAbs) and the fluorescence emission maxima (λEm) and the quantum yields (φ) of some coumarin-3-ylcarbonyl aminoxy acid conjugates were comparable to those of the analogous amino acid derivatives.

Original languageEnglish (US)
Pages (from-to)83-90
Number of pages8
Issue number1
StatePublished - 2011

Bibliographical note

Copyright 2011 Elsevier B.V., All rights reserved.


  • acylations
  • amino acids
  • aminoxy acids
  • fluorescence
  • peptides


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