Abstract
Functional metagenomics was used to search for florfenicol resistance genes in libraries of cloned DNA isolated from Alaskan soil. A gene that mediated reduced susceptibility to florfenicol was identified and designated pexA. The predicted PexA protein showed a structure similar to that of efflux pumps of the major facilitator superfamily.
Original language | English (US) |
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Pages (from-to) | 5321-5326 |
Number of pages | 6 |
Journal | Applied and environmental microbiology |
Volume | 76 |
Issue number | 15 |
DOIs | |
State | Published - Aug 2010 |