Novel activity of rhodobacter sphaeroides spheroidene monooxygenase CrtA expressed in escherichia coli

Pyung Cheon Lee, Erik Holtzapple, Claudia Schmidt-Dannert

Research output: Contribution to journalArticlepeer-review

13 Scopus citations

Abstract

The spheroidene monooxygenase CrtA of Rhodobacter sphaeroides introduces a keto group and/or hydroxy group at the ends of nonnative substrates in Escherichia coli, resulting in the production of novel oxocarotenoids.The heme-containing CrtA is not a P450 enzyme but a new type of oxygenase.

Original languageEnglish (US)
Pages (from-to)7328-7331
Number of pages4
JournalApplied and environmental microbiology
Volume76
Issue number21
DOIs
StatePublished - Nov 2010

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