Norwalk virus enteric illness acquired by swimming exposure

James S. Koopman, Edward A. Eckert, Harry B. Greenberg, Brian C. Strohm, Richard E. Isaacson, Arnold S. Monto

Research output: Contribution to journalArticle

52 Citations (Scopus)

Abstract

In an epidemic of gastrointestinal illness strongly associated with swimming at a recreational park in Macomb County, Michigan, in July, 1979, the authors demonstrated the value of serologic testing to detect Norwalk virus infection. Rises in antibody titer to Norwalk virus were noted in all 11 individuals tested. Electron microscopy on stools from 20 III individuals revealed only one with Norwalk virus-like particles. This particle was shown by radioimmunoassay and immune electron microscopy not to be Norwalk virus and not to have stimulated detectable antibodies in this individual. These results not only indicate that electron microscopy is insensitive in detecting Norwalk virus, but that it has the potential to mislead. A low rate of respiratory symptoms was associated with gastrointestinal illness in this Norwalk virus out break. The route of exposure might have been important for this. The outbreak was also noteworthy in that, although there was evidence of familial clusters of resistance, a very high percentage of the population was proved to be susceptible to the Norwalk virus.

Original languageEnglish (US)
Pages (from-to)173-177
Number of pages5
JournalAmerican journal of epidemiology
Volume115
Issue number2
DOIs
StatePublished - Feb 1982

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Norwalk virus
Electron Microscopy
Antibodies
Virus Diseases
Respiratory Rate
Virion
Radioimmunoassay
Disease Outbreaks

Keywords

  • Diarrhea
  • Gastroenteritis
  • Microscopy electron
  • Radioimmunoassay
  • Viruses

Cite this

Koopman, J. S., Eckert, E. A., Greenberg, H. B., Strohm, B. C., Isaacson, R. E., & Monto, A. S. (1982). Norwalk virus enteric illness acquired by swimming exposure. American journal of epidemiology, 115(2), 173-177. https://doi.org/10.1093/oxfordjournals.aje.a113288

Norwalk virus enteric illness acquired by swimming exposure. / Koopman, James S.; Eckert, Edward A.; Greenberg, Harry B.; Strohm, Brian C.; Isaacson, Richard E.; Monto, Arnold S.

In: American journal of epidemiology, Vol. 115, No. 2, 02.1982, p. 173-177.

Research output: Contribution to journalArticle

Koopman, JS, Eckert, EA, Greenberg, HB, Strohm, BC, Isaacson, RE & Monto, AS 1982, 'Norwalk virus enteric illness acquired by swimming exposure', American journal of epidemiology, vol. 115, no. 2, pp. 173-177. https://doi.org/10.1093/oxfordjournals.aje.a113288
Koopman, James S. ; Eckert, Edward A. ; Greenberg, Harry B. ; Strohm, Brian C. ; Isaacson, Richard E. ; Monto, Arnold S. / Norwalk virus enteric illness acquired by swimming exposure. In: American journal of epidemiology. 1982 ; Vol. 115, No. 2. pp. 173-177.
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