Noroleanane-type triterpenoids from Dolichos trilobus L. and their anti-α-glucosidase activities

Ming Luo, Yan Hong Li, Ya Lu, Yan Yuan, Rong Sheng Ruan, Yong Ming Chuan, Kai Tian, Xiang Zhong Huang

Research output: Contribution to journalArticle

2 Scopus citations

Abstract

Falcatane A (1) and B (2), 4-oxo-3,24-dinor-2,4-secooleanane- and 3-oxo-24- noroleanane-type triterpenoids, together with seven known triterpenoids involving 2-hydroxy-3-oxo-24-noroleana-1,4,12-trien-28-oic acid (3) and oleanolic acid (4), were separated from the ethyl acetate roots extract of Dolichos trilobus using the column chromatography of silica gel, MCI gel, and Sephadex LH-20. The compounds were determined by analysis of IR, NMR spectroscopic data and mass spectrometry. In the bioassay, all isolates showed varying degree of the α-glucosidase inhibitory activity except compound 2.

Original languageEnglish (US)
JournalNatural Product Research
DOIs
StateAccepted/In press - Jan 1 2019
Externally publishedYes

Keywords

  • Dolichos trilobusL
  • anti-α-glucosidase activity
  • nortriterpenoids

PubMed: MeSH publication types

  • Journal Article

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