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Nonviral Gene Delivery with Cationic Glycopolymers
Craig Van Bruggen
, Joseph K. Hexum
, Zhe Tan
, Rishad J. Dalal
,
Theresa M. Reineke
Chemistry (Twin Cities)
Research output
:
Contribution to journal
›
Article
›
peer-review
144
Scopus citations
Overview
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Keyphrases
Addition-fragmentation Chain Transfer
40%
Biocompatibility
40%
Biological Systems
20%
Carbohydrate Polymers
20%
Carbohydrates
60%
Cargo
60%
Cationic Glycopolymers
100%
Cationic Polymer
20%
Chain Transfer Polymerization
20%
Chemical Base
20%
Colloidal Stability
60%
Colloidal Stabilization
20%
Copolymer
20%
Diblock Copolymer
20%
Diblock Polymer
20%
Disaccharides
20%
Efficient Delivery
40%
Ethyleneimine
20%
FDA-approved Drugs
20%
Full Potential
20%
Gene Editing
20%
Gene Expression
20%
Gene Therapy
60%
Gene-gene
20%
Glycopolymer
100%
Hepatocytes
20%
Human Cells
20%
Hydrophilic Shell
20%
Immunocompatibility
20%
In Situ
20%
Linear Polyamidoamines
20%
Liver
20%
Liver Targeting
20%
Lyophilization
40%
Monosaccharides
40%
N-acetylgalactosamine
20%
Non-native
20%
Non-viral Gene Delivery
100%
Nucleic Acids
60%
PEG Functionalization
20%
Plasmid
20%
Plasmid DNA (pDNA)
20%
Polycationic
20%
Polymer Yield
20%
Polymer-based
20%
Polymeric Drug Delivery Systems
20%
Polyplexes
20%
Radical Addition
40%
Receptor-mediated Uptake
20%
Reconstitution
20%
Safe Delivery
40%
Shelf Life
20%
Small Interfering RNA (siRNA)
20%
Step-growth
40%
Step-growth Polymerization
20%
Structure-activity Relationship
20%
Tissue Targeting
20%
Transfection Reagent
40%
Transfer Techniques
20%
Trehalose
40%
Tunability
20%
Vehicle Degradation
20%
Vinyl
20%
Viral Vectors
20%
Biochemistry, Genetics and Molecular Biology
Complex Formation
33%
Disaccharide
33%
Galactosamine
33%
Gene Expression
33%
Gene Therapy
100%
Genome Editing
33%
Hepatocyte
33%
Monosaccharides
66%
Nonviral Gene Delivery System
100%
Nucleic Acid
100%
Plasmid
66%
Small Interfering RNA
33%
Structure Activity Relation
33%
Transfection
100%
Trehalose
66%
Virus Vector
33%
Pharmacology, Toxicology and Pharmaceutical Science
Biocompatibility
33%
Complexation
33%
Copolymer
66%
Disaccharide
33%
Gene Delivery
100%
Monomer
33%
Monosaccharide
66%
N Acetylgalactosamine
33%
Nucleic Acid
100%
Plasmid DNA
33%
Polyamine
33%
Polyethylene Glycol
33%
Receptor
33%
Small Interfering RNA
33%
Structure Activity Relationship
33%
Trehalose
66%
Viral Vector
33%
Material Science
Biocompatibility
33%
Complexation
33%
Copolymer
66%
Gene Expression
33%
Gene Therapy
100%
Nucleic Acid
100%
Plasmid
66%
Polyethylene Glycol
33%
Polymerization
33%
Step-Growth Polymerization
33%