Nonlinear dynamics of periodically paced cardiac tissue

Elena G. Tolkacheva, Xiaopeng Zhao

Research output: Contribution to journalReview article

9 Citations (Scopus)

Abstract

This manuscript reviews various experimental methods and mathematical approaches for nonlinear dynamics of paced cardiac tissue. A particular focus is on cardiac alternans. Several mapping models are introduced to predict alternans at the cellular level. Experimental observations and modeling approaches are introduced to understand mechanisms of alternans formation in extended heart tissue. In addition, potential bifurcation mechanisms of alternans and the underlying interplay between calcium and voltage dynamics are discussed.

Original languageEnglish (US)
Pages (from-to)347-363
Number of pages17
JournalNonlinear Dynamics
Volume68
Issue number3
DOIs
StatePublished - May 1 2012

Fingerprint

Cardiac
Nonlinear Dynamics
Tissue
Calcium
Bifurcation
Voltage
Predict
Electric potential
Modeling
Model
Observation
Review
Heart

Keywords

  • Action potential duration
  • Alternans
  • Bifurcations
  • Restitution

Cite this

Nonlinear dynamics of periodically paced cardiac tissue. / Tolkacheva, Elena G.; Zhao, Xiaopeng.

In: Nonlinear Dynamics, Vol. 68, No. 3, 01.05.2012, p. 347-363.

Research output: Contribution to journalReview article

Tolkacheva, Elena G. ; Zhao, Xiaopeng. / Nonlinear dynamics of periodically paced cardiac tissue. In: Nonlinear Dynamics. 2012 ; Vol. 68, No. 3. pp. 347-363.
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