Noninvasive test for tuberculosis detection among primates

Tiffany M. Wolf, Lawrence Mugisha, Fernanda Miyagaki Shoyama, Melanie J. O ’ Malley, Joanne L. Flynn, Benon Asiimwe, Dominic A. Travis, Randall S. Singer, Srinand Sreevatsan

Research output: Contribution to journalArticlepeer-review

5 Scopus citations

Abstract

Traditional testing methods have limited epidemiologic studies of tuberculosis among free-living primates. PCR amplifcation of insertion element IS6110 of Mycobacterium tuberculosis from fecal samples was evaluated as a noninvasive screening test for tuberculosis in primates. Active tuberculosis was detected among inoculated macaques and naturally exposed chimpanzees, demonstrating the utility of this test.

Original languageEnglish (US)
Pages (from-to)468-470
Number of pages3
JournalEmerging infectious diseases
Volume21
Issue number3
DOIs
StatePublished - 2015

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