Noninvasive localization of the site of origin of paced cardiac activation in human by means of a 3-D heart model

Guanglin Li; Xin Zhang; Jie Lian; Bin He

doi:10.1109/TBME.2003.816068

Noninvasive localization of the site of origin of paced cardiac activation in human by means of a 3-D heart model

Guanglin Li, Xin Zhang, Jie Lian, Bin He

Biomedical Engineering

Research output: Contribution to journal › Article › peer-review

15 Scopus citations

Abstract

A recently developed heart-model-based localization approach is experimentally evaluated in noninvasively localizing the site of origin of cardiac activation in a patient with a pacemaker. The heart-torso model of the patient was constructed from the contrast ultrafast computed tomography images. The site of initial paced activation in the patient was quantitatively localized and compared with the tip position of the pacemaker lead. The localization error of the inverse estimation was found to be 5.2 mm with respect to the true lead tip position. The promising result of this pilot experimental study suggests the feasibility of localizing the site of origin of cardiac activation in an experimental setting. The heart-model-based localization approach may become an alternative tool in localizing the site of origin of cardiac activation.

Original language	English (US)
Pages (from-to)	1117-1120
Number of pages	4
Journal	IEEE Transactions on Biomedical Engineering
Volume	50
Issue number	9
DOIs	https://doi.org/10.1109/TBME.2003.816068
State	Published - Sep 1 2003

Bibliographical note

Funding Information:
Manuscript received April 12, 2002; revised February 14, 2003. This work was supported in part by American Heart Association under Grant 0140132N, in part by the National Science Foundation (NSF) under Grant BES-0201939 and NSF CAREER Award BES-9875344, and in part by the National Institutes of Health (NIH) under Grant R01EB00178. Asterisk indicates corresponding author.

Keywords

Body surface potential map
Cardiac activation
Electrocardiographic inverse problem
Pace mapping

Access

10.1109/TBME.2003.816068

Cite this

@article{34580c797f0b4c098c4c02189671bb73,

title = "Noninvasive localization of the site of origin of paced cardiac activation in human by means of a 3-D heart model",

abstract = "A recently developed heart-model-based localization approach is experimentally evaluated in noninvasively localizing the site of origin of cardiac activation in a patient with a pacemaker. The heart-torso model of the patient was constructed from the contrast ultrafast computed tomography images. The site of initial paced activation in the patient was quantitatively localized and compared with the tip position of the pacemaker lead. The localization error of the inverse estimation was found to be 5.2 mm with respect to the true lead tip position. The promising result of this pilot experimental study suggests the feasibility of localizing the site of origin of cardiac activation in an experimental setting. The heart-model-based localization approach may become an alternative tool in localizing the site of origin of cardiac activation.",

keywords = "Body surface potential map, Cardiac activation, Electrocardiographic inverse problem, Pace mapping",

author = "Guanglin Li and Xin Zhang and Jie Lian and Bin He",

note = "Funding Information: Manuscript received April 12, 2002; revised February 14, 2003. This work was supported in part by American Heart Association under Grant 0140132N, in part by the National Science Foundation (NSF) under Grant BES-0201939 and NSF CAREER Award BES-9875344, and in part by the National Institutes of Health (NIH) under Grant R01EB00178. Asterisk indicates corresponding author.",

year = "2003",

month = sep,

day = "1",

doi = "10.1109/TBME.2003.816068",

language = "English (US)",

volume = "50",

pages = "1117--1120",

journal = "IRE transactions on medical electronics",

issn = "0018-9294",

publisher = "IEEE Computer Society",

number = "9",

}

TY - JOUR

T1 - Noninvasive localization of the site of origin of paced cardiac activation in human by means of a 3-D heart model

AU - Li, Guanglin

AU - Zhang, Xin

AU - Lian, Jie

AU - He, Bin

N1 - Funding Information: Manuscript received April 12, 2002; revised February 14, 2003. This work was supported in part by American Heart Association under Grant 0140132N, in part by the National Science Foundation (NSF) under Grant BES-0201939 and NSF CAREER Award BES-9875344, and in part by the National Institutes of Health (NIH) under Grant R01EB00178. Asterisk indicates corresponding author.

PY - 2003/9/1

Y1 - 2003/9/1

N2 - A recently developed heart-model-based localization approach is experimentally evaluated in noninvasively localizing the site of origin of cardiac activation in a patient with a pacemaker. The heart-torso model of the patient was constructed from the contrast ultrafast computed tomography images. The site of initial paced activation in the patient was quantitatively localized and compared with the tip position of the pacemaker lead. The localization error of the inverse estimation was found to be 5.2 mm with respect to the true lead tip position. The promising result of this pilot experimental study suggests the feasibility of localizing the site of origin of cardiac activation in an experimental setting. The heart-model-based localization approach may become an alternative tool in localizing the site of origin of cardiac activation.

AB - A recently developed heart-model-based localization approach is experimentally evaluated in noninvasively localizing the site of origin of cardiac activation in a patient with a pacemaker. The heart-torso model of the patient was constructed from the contrast ultrafast computed tomography images. The site of initial paced activation in the patient was quantitatively localized and compared with the tip position of the pacemaker lead. The localization error of the inverse estimation was found to be 5.2 mm with respect to the true lead tip position. The promising result of this pilot experimental study suggests the feasibility of localizing the site of origin of cardiac activation in an experimental setting. The heart-model-based localization approach may become an alternative tool in localizing the site of origin of cardiac activation.

KW - Body surface potential map

KW - Cardiac activation

KW - Electrocardiographic inverse problem

KW - Pace mapping

UR - http://www.scopus.com/inward/record.url?scp=0041317195&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=0041317195&partnerID=8YFLogxK

U2 - 10.1109/TBME.2003.816068

DO - 10.1109/TBME.2003.816068

M3 - Article

C2 - 12943279

AN - SCOPUS:0041317195

VL - 50

SP - 1117

EP - 1120

JO - IRE transactions on medical electronics

JF - IRE transactions on medical electronics

SN - 0018-9294

IS - 9

ER -

Noninvasive localization of the site of origin of paced cardiac activation in human by means of a 3-D heart model

Abstract

Bibliographical note

Keywords

Access

Other files and links

Fingerprint

Cite this