Nonheme Iron Centers in Oxygen Activation: Characterization of an Iron(III) Hydroperoxide Intermediate

Marcel Lubben; Auke Meetsma; Elizabeth C. Wilkinson; Ben Feringa; Lawrence Que

doi:10.1002/anie.199515121

Nonheme Iron Centers in Oxygen Activation: Characterization of an Iron(III) Hydroperoxide Intermediate

Marcel Lubben
, Auke Meetsma
, Elizabeth C. Wilkinson
, Ben Feringa
, Lawrence Que

Chemistry (Twin Cities)

Research output: Contribution to journal › Article › peer-review

253 Scopus citations

Abstract

A new pentadentate nitrogen ligand facilitates the synthesis of a low‐spin iron(II) complex, which reacts with H₂O₂ at low temperature to form the transient purple complex 1. Complex 1 was formulated as an Fe^IIIOOH complex, the first synthetic example of such a species to be characterized by electrospray ionization mass spectrometry. Furthermore, 1 oxidizes cyclohexane efficiently, thus supporting the notion that an Fe^IIIOOH moiety can participate in oxygen activation mechanisms of nonheme iron enzymes. (Figure Presented.)

Original language	English (US)
Pages (from-to)	1512-1514
Number of pages	3
Journal	Angewandte Chemie International Edition in English
Volume	34
Issue number	13-14
DOIs	https://doi.org/10.1002/anie.199515121
State	Published - Jul 31 1995

Keywords

electrospray mass spectrometry
hydroperoxide compounds
nonheme iron compounds
oxygen activation

Publisher link

10.1002/anie.199515121

Find It

Find It at U of M Libraries

Cite this

@article{6939593375774d9a9914058d454956bc,

title = "Nonheme Iron Centers in Oxygen Activation: Characterization of an Iron(III) Hydroperoxide Intermediate",

abstract = "A new pentadentate nitrogen ligand facilitates the synthesis of a low‐spin iron(II) complex, which reacts with H2O2 at low temperature to form the transient purple complex 1. Complex 1 was formulated as an FeIIIOOH complex, the first synthetic example of such a species to be characterized by electrospray ionization mass spectrometry. Furthermore, 1 oxidizes cyclohexane efficiently, thus supporting the notion that an FeIIIOOH moiety can participate in oxygen activation mechanisms of nonheme iron enzymes. (Figure Presented.)",

keywords = "electrospray mass spectrometry, hydroperoxide compounds, nonheme iron compounds, oxygen activation",

author = "Marcel Lubben and Auke Meetsma and Wilkinson, \{Elizabeth C.\} and Ben Feringa and Lawrence Que",

year = "1995",

month = jul,

day = "31",

doi = "10.1002/anie.199515121",

language = "English (US)",

volume = "34",

pages = "1512--1514",

journal = "Angewandte Chemie International Edition in English",

issn = "0570-0833",

publisher = "John Wiley and Sons Ltd",

number = "13-14",

}

TY - JOUR

T1 - Nonheme Iron Centers in Oxygen Activation

T2 - Characterization of an Iron(III) Hydroperoxide Intermediate

AU - Lubben, Marcel

AU - Meetsma, Auke

AU - Wilkinson, Elizabeth C.

AU - Feringa, Ben

AU - Que, Lawrence

PY - 1995/7/31

Y1 - 1995/7/31

N2 - A new pentadentate nitrogen ligand facilitates the synthesis of a low‐spin iron(II) complex, which reacts with H2O2 at low temperature to form the transient purple complex 1. Complex 1 was formulated as an FeIIIOOH complex, the first synthetic example of such a species to be characterized by electrospray ionization mass spectrometry. Furthermore, 1 oxidizes cyclohexane efficiently, thus supporting the notion that an FeIIIOOH moiety can participate in oxygen activation mechanisms of nonheme iron enzymes. (Figure Presented.)

AB - A new pentadentate nitrogen ligand facilitates the synthesis of a low‐spin iron(II) complex, which reacts with H2O2 at low temperature to form the transient purple complex 1. Complex 1 was formulated as an FeIIIOOH complex, the first synthetic example of such a species to be characterized by electrospray ionization mass spectrometry. Furthermore, 1 oxidizes cyclohexane efficiently, thus supporting the notion that an FeIIIOOH moiety can participate in oxygen activation mechanisms of nonheme iron enzymes. (Figure Presented.)

KW - electrospray mass spectrometry

KW - hydroperoxide compounds

KW - nonheme iron compounds

KW - oxygen activation

UR - https://www.scopus.com/pages/publications/33748216512

UR - https://www.scopus.com/pages/publications/33748216512#tab=citedBy

U2 - 10.1002/anie.199515121

DO - 10.1002/anie.199515121

M3 - Article

AN - SCOPUS:33748216512

SN - 0570-0833

VL - 34

SP - 1512

EP - 1514

JO - Angewandte Chemie International Edition in English

JF - Angewandte Chemie International Edition in English

IS - 13-14

ER -

Nonheme Iron Centers in Oxygen Activation: Characterization of an Iron(III) Hydroperoxide Intermediate

Abstract

Keywords

Publisher link

Find It

Other files and links

Fingerprint

Cite this