The use of high-intensity focused ultrasound for cancer therapy and tissue ablation has been receiving increased attention recently. Feedback for these treatments has been limited to invasive fine-wire thermocouple arrays. These are impractical in many clinical situations. For this purpose, a new non-invasive feedback method for ultrasound thermotherapy has been developed which is based on the estimation of a fundamental frequency f1. The value of f1 is a function of the average scatterer spacing and the local value of the speed of sound in the tissue, both of which are functions of temperature. It is computed from an A-line which is acquired using pulse-echo diagnostic ultrasound imaging the tissue zone being heated. Experimental results demonstrating quantitative, non-invasive temperature change measurements caused by a 192-element ultrasound phased array, as well as the underlying mathematical model, are shown.
|Original language||English (US)|
|Number of pages||2|
|Journal||Annual International Conference of the IEEE Engineering in Medicine and Biology - Proceedings|
|State||Published - Dec 1 1995|