Non-invasive monitoring of stromal biophysics with targeted depletion of hyaluronan in pancreatic ductal adenocarcinoma

Keyphrases

• Hyaluronan 100%
• Biophysics 100%
• Non-invasive Monitoring 100%
• Pancreatic Ductal Adenocarcinoma 100%
• Multiparametric MRI (mpMRI) 33%
• Collagen 33%
• Glycosaminoglycan Chemical Exchange Saturation Transfer 33%
• Vasculature 16%
• Solid Tumors 16%
• Tesla 16%
• PEGylated 16%
• Small Molecules 16%
• Glycosaminoglycans 16%
• Perfusion 16%
• PEGPH20 16%
• Recombinant Human Hyaluronidase 16%
• Therapeutic Response 16%
• Immune Cells 16%
• Non-invasive Device 16%
• Physical Barrier 16%
• Apparent Diffusion Coefficient 16%
• Stromal Reaction 16%
• Spin Relaxation Time 16%
• Replenishment 16%
• T2 Value 16%
• Tumor Perfusion 16%
• Phantom Imaging 16%
• Fibroinflammatory Disease 16%
• Activated Fibroblasts 16%
• Transfer Value 16%

Biochemistry, Genetics and Molecular Biology

• Restylane 100%
• Glycosaminoglycan 50%
• Magnetic Resonance Imaging 33%
• Chemical Exchange Saturation Transfer 33%
• Perfusion 33%
• Facilitated Diffusion 16%
• Vascularization 16%
• Immunocompetent Cell 16%
• Apparent Diffusion Coefficient 16%
• Hyaluronidase 16%
• Fibroblast 16%