Non-invasive estimation of myocardial infarction by means of a heart-model-based imaging approach: A simulation study

G. Li, Bin He

Research output: Contribution to journalArticle

26 Scopus citations

Abstract

In the study, a new myocardial infarction (MI) estimation method was developed for estimating MI in the three-dimensional myocardium by means of a heart-model-based inverse approach. The site and size of MI are estimated from body surface electrocardiograms by minimising multiple objective functions of the measured body surface potential maps (BSPMs) and the heart-model-generated BSPMs. Computer simulations were conducted to evaluate the performance of the developed method, using a single-site MI and dual-site MI protocols. The simulation results show that, for the single-site MI, the averaged spatial distance (SD) between the weighting centres of the 'true' and estimated MIs, and the averaged relative error (RE) between the numbers of the 'true' and estimated infarcted units are 3.0±0.6/3.6±0.6mm and 0.11±0.02/0.14±0.02, respectively, when 5μV/10μV Gaussian white noise was added to the body surface potentials. For the dual-site MI, the averaged SD between the weighting centres of the 'true' and estimated MIS, and the averaged RE between the numbers of the 'true' and estimated infarcted units are 3.8±0.7/3.9±0.7 mm and 0.12±0.02/0.14±0.03, respectively, when 5μV/10μV Gaussian white noise was added to the body surface potentials. The simulation results suggest the feasibility of applying the heart-model-based imaging approach to the estimation of myocardial infarction from body surface potentials.

Original languageEnglish (US)
Pages (from-to)128-136
Number of pages9
JournalMedical and Biological Engineering and Computing
Volume42
Issue number1
DOIs
StatePublished - Jan 1 2004

Keywords

  • Body surface potential maps
  • Electro-cardiographic imaging
  • Electrocardiographic inverse problem
  • Heart model
  • Myocardial infarction

Fingerprint Dive into the research topics of 'Non-invasive estimation of myocardial infarction by means of a heart-model-based imaging approach: A simulation study'. Together they form a unique fingerprint.

  • Cite this