Abstract
We report a case of non-immune hydrops fetalis (NIHF) caused by herpes simplex virus type 2 (HSV-2) in an infant whose mother had recurrent HSV-2 infection. In spite of prematurity, severe disseminated infection and hydrops, the infant survived and was neurologically intact. HSV-2-induced NIHF is extremely rare, particularly in the setting of recurrent maternal infection, and this case is, to our knowledge, the first report of a surviving infant. HSV-2 should be considered in the differential diagnosis of NIHF and early initiation of empiric acyclovir therapy is recommended in this setting, pending the results of virologic diagnostic tests.
Original language | English (US) |
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Pages (from-to) | 817-820 |
Number of pages | 4 |
Journal | Journal of Perinatology |
Volume | 33 |
Issue number | 10 |
DOIs | |
State | Published - Oct 2013 |
Keywords
- Acyclovir
- Fetal hydrops
- HSV-2 infection
- Neonatal HSV infection
- Placental infection
- Torch infection