Nociceptive aspects of fibromyalgia.

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Although characterized by a variety of symptoms, chronic widespread pain is the primary complaint bringing most patients with fibromyalgia syndrome (FMS) into the clinic. The etiology of this painful condition is unknown, and any possible relationship between pain and the many other symptoms of FMS is unclear. This article focuses on the unique characteristics of nociception in patients with FMS. The intent is to present criteria that should be considered in the search for biological events that contribute to FMS pain. Based on this approach, examples are proposed of factors that fulfill some criteria and may, therefore, deserve further study for their possible role in pain associated with FMS.

Original languageEnglish (US)
Pages (from-to)338-346
Number of pages9
JournalCurrent pain and headache reports
Issue number4
StatePublished - Aug 2001

Bibliographical note

Funding Information:
The work involved with this manuscript was supported by NIH grants NS39740 (A.A.L.) funded by the National Institute of Neurological Disorders and Stroke and the National Institutes on Arthritis and Musculoskeletal and Skin Diseases and by DA07234 (K.J.K.) funded by the National Institute on Drug Abuse.


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