No effect of exercise on urinary 6-sulfatoxymelatonin and catecholamines in young women participating in a 16-week randomized controlled trial

Andrea Y. Arikawa, William Thomas, Sanjay R. Patel, Mindy S. Kurzer

Research output: Contribution to journalArticle

6 Scopus citations

Abstract

Background: Womenwith breast cancer have decreased levels of melatonin or its metabolite in plasma and/ or urine. Methods:Wemeasured serum melatonin, urinary 6-sulfatoxymelatonin, catecholamines, and cortisol in 141 sedentary young female participants in a clinical trial comparing 150 min/wk aerobic exercise for 4 months to no-exercise controls. Demographics, health surveys, body composition, sleep quality, fitness levels, and blood and urine samples were obtained at baseline and 16 weeks. Results: There were no differences between groups at baseline in demographics, exercise, sleep habits, or study hormones. There were also no significant differences between groups in any of the hormones at 16 weeks. Conclusion: Sixteen weeks of exercise had minimal effects on melatonin secretion of young women. Impact: There is convincing evidence that exercise protects against breast cancer, but this does not appear to occur through changes in melatonin secretion.

Original languageEnglish (US)
Pages (from-to)1634-1636
Number of pages3
JournalCancer Epidemiology Biomarkers and Prevention
Volume22
Issue number9
DOIs
StatePublished - Sep 2013

Fingerprint Dive into the research topics of 'No effect of exercise on urinary 6-sulfatoxymelatonin and catecholamines in young women participating in a 16-week randomized controlled trial'. Together they form a unique fingerprint.

  • Cite this