Abstract
Oxidative decarboxylative arylation reactions are potentially attractive routes to generate biaryl structures from simple and readily available precursors; yet, they are underutilized, because of limitations in the carboxylic acid scope. Here, we report a nickel catalyst system that enables the selective decarboxylative arylation of unactivated C-H bonds with a broad scope of (hetero)aromatic carboxylate coupling partners. Preliminary mechanistic insights suggest that the efficiency and selectivity of this protocol originate from cooperation between Ni and Ag.
Original language | English (US) |
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Pages (from-to) | 4597-4601 |
Number of pages | 5 |
Journal | ACS Catalysis |
Volume | 7 |
Issue number | 7 |
DOIs | |
State | Published - Jul 7 2017 |
Externally published | Yes |
Bibliographical note
Publisher Copyright:© 2017 American Chemical Society.
Keywords
- C-H activation
- decarboxylation
- heteroaryl
- nickel
- silver