NHLBI clinical trials and conflicts of interest

Henry Buchwald

Research output: Contribution to journalEditorialpeer-review

1 Scopus citations
Original languageEnglish (US)
Pages (from-to)217-222
Number of pages6
JournalControlled clinical trials
Issue number4
StatePublished - Aug 1990

Bibliographical note

Funding Information:
Traditionally, the NHLBI has sought to initiate and support trails via a variety of mechanisms. Among the extramural lipid/atherosclerosis trials funded by the NHLBI, the Minnesota Coronary Survey \[5\]t, he Coronary Drug Project (CDP) \[6\]t, he Cholesterol Lowering Atherosclerosis Study (CLAS) \[7\]a, nd the Program on Surgical Control of the Hyperlipidemias (POSCH) \[8\]a, re all examples of investigator-initiated, grant-funded trials. Examples of institute-initiated, contract-funded trials include the Multiple R~sk Factor Intervention TRIAL (MRFIT) \[9\]t,h e Lipid Research Clinics-Coronary Primary Prevention Trial (LRC-CPPT) \[10\]a, nd the Post-Coronary Artery Bypass Graft (Post-CABG) Trial \[11\]T. he recent request for application (RFA) from the NHLBI for a multicenter study of postprandial lipoproteins and atherosclerosis would modify grant funding via a cooperative agreement.

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